The Tian Research Group

Welcome to the PChem-Bioelectronics group

 

A lab dedicated to advancements in photoelectroceuticals and living bioelectronics

 

At the Tian Group, we blend physical chemistry with bioelectronics to forge drug‐free, cell‐based, and non‐genetic therapeutic strategies that pave the way for sustainable healthcare. By applying the principles of physical chemistry, we develop diverse electronics‐enabled biointerfaces that mimic cellular behaviors, harnessing both classical and quantum phenomena for precise, real‐time control of cellular electrophysiology. Our work has yielded advanced biophysical tools that offer unprecedented insight into subcellular processes without relying on conventional pharmacological methods.

We pioneered the concept of photoelectroceuticals and developed a range of platforms that enable the study of electrophysiology across multiple biological scales with high temporal resolution using optical methods. Since 2012, we have led advancements in living electronics, designing composite materials that not only integrate with biological systems but also adapt and respond like natural entities. Looking ahead, we are committed to shaping a future where our innovations drive breakthroughs in healing, environmental sustainability, and scientific exploration. We believe that the future of sensing and modulation technologies should embrace the “Form Follows Fiction” philosophy—where design is driven not only by practical functionality but also by creative imagination and the compelling human-centered stories behind each innovation—rather than adhering solely to “Form Follows Function”.

“When you are enthusiastic about what you do, you feel this positive energy. It’s very simple.”

Paulo Coelho, the author of “The Alchemist”

 

“The only metrics that will truly matter to my life are the individuals whom I have been able to help, one by one, to become better people.”

Clayton M. Christensen, in “How Will You Measure Your Life?”.

 

 

Group Highlights

Featured Alumni

Warmest congratulations to our former lab member, Dr. John Zimmerman, on accepting a faculty position in the Meinig School of Biomedical Engineering at Cornell University! During his time as a graduate student in our lab, John played a pivotal role in pioneering intracellular photostimulation. We’re incredibly proud of his accomplishments and excited to see the innovative work he will lead in this new chapter of his career!

Featured Alumni

Warmest congratulations to our former lab member, Professor Yuanwen Jiang, on being named one of the MIT Technology Review TR35 China honorees! This prestigious recognition celebrates his exceptional contributions to science and technology as one of the top young innovators under 35!

Featured Alumni

Warmest congratulations to our former lab member, Professor Menahem Rotenberg, for receiving the prestigious Krill Prize for Excellence in Scientific Research from the Wolf Foundation!

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