The Tian Research Group

Welcome to the PChem-Bioelectronics group

 

A lab dedicated to advancements in photoelectroceuticals and living bioelectronics

 

At the Tian Group, we blend physical chemistry with bioelectronics to forge drug‐free, cell‐based, and non‐genetic therapeutic strategies that pave the way for sustainable healthcare. By applying the principles of physical chemistry, we develop diverse electronics‐enabled biointerfaces that mimic cellular behaviors, harnessing both classical and quantum phenomena for precise, real‐time control of cellular electrophysiology. Our work has yielded advanced biophysical tools that offer unprecedented insight into subcellular processes without relying on conventional pharmacological methods.

We pioneered the concept of photoelectroceuticals and developed a range of platforms that enable the study of electrophysiology across multiple biological scales with high temporal resolution using optical methods. Since 2012, we have led advancements in living electronics, designing composite materials that not only integrate with biological systems but also adapt and respond like natural entities. Looking ahead, we are committed to shaping a future where our innovations drive breakthroughs in healing, environmental sustainability, and scientific exploration.

“When you are enthusiastic about what you do, you feel this positive energy. It’s very simple.”

Paulo Coelho, the author of “The Alchemist”

 

“The only metrics that will truly matter to my life are the individuals whom I have been able to help, one by one, to become better people.”

Clayton M. Christensen, in “How Will You Measure Your Life?”.

 

 

Group Highlights

Featured Lab Members

Changxu Sun is advancing sustainable biointerface biomaterials and electronics by harnessing essential components extracted from plant waste. His latest paper was even showcased as the cover feature in Matter!

Featured News

Chuanwang has been pioneering e-sustainability in our lab, driving innovations with far-reaching implications for healthcare, climate change, and the future of the electronics industry.

Featured Publications

In a recent episode of UChicago’s Big Brains podcast, Bozhi Tian shared his outlook on the future of bioelectronics, exploring its potential far beyond biomedical applications. He also spotlighted three publications from his lab—the optical cardiac pacemaker, living bioelectronics, and the antimicrobial patch!

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